Description
Ebolavirus (EBOV) glycoprotein (GP) is the only virally expressed protein on the virion surface and is critical for attachment to host cells and catalysis of membrane fusion. The EBOV GP is a critical component of vaccines as well as a target of neutralizing antibodies and inhibitors of attachment and fusion.
Ebolavirus Glycoprotein (Sudan strain) (click to see its protein sequence) Viral Like Particles was packaged in HEK293T cells using our proprietary technology. It is the replication-incompetent particles in which the Ebolavirus Envelope (with 6His-tag at its C-terminal) was pseudo-typed as the lentiviral particles’ surface envelope protein. [Note: This VLP has the Ebolavirus Envelope antigen expressed on the particle’s surface. If you want to over-express the Ebolavirus Envelope antigen in your desired cell types, please use lentivirus product, CAT#: LVP1408-PBS.]
This VLP packaged a non-sense sequence (Null) as the particle’s virion genomic material, to maintain the intact of the particles.
Applications:
Ebolavirus Glycoprotein /Envelope was assembled as surface antigens which can be used as the ready to use Ebolavirus Envelope antigen, or for raising the specific antibodies, for the validation of anti-Ebolavirus Envelope antibodies, in vaccine development and other validation assays. This VLP can also be detected by the anti-C-terminal 6His-tag antibody.
The VLP’s titer was measured via ELISA P24 assay. Every single particle assembled many envelope molecules at its surface. See more details in Product Manual.
Amount: 200ul/vial at 1×108 VP/ml.
CAT#: VLP009
