Description
Zika virions are comprised of an envelope and a nucleocapsid. The structural proteins include a capsid (C) protein, a glycoprotein precursor (preM) which is split into the Pr protein and the M protein, and an envelope (E) protein.
Zika Envelope (click to see its protein sequence) Viral Like Particles was packaged in HEK293T cells using our proprietary technology. It is the replication-incompetent particles in which the Zika Envelope (with 6His-tag at its C-terminal) was pseudo-typed as the lentiviral particles’ surface envelope protein. [Note: This VLP has the Zika Envelope antigen expressed on the particle’s surface. If you want to over-express the Zika Envelope antigen in your desired cell types, please use lentivirus product, CAT#: LVP1404-PBS.]
This VLP packaged a non-sense sequence (Null) as the particle’s virion genomic material, to maintain the intact of the particles.
Applications:
Zika Envelope was assembled as surface antigens which can be used as the ready to use Zika Envelope antigen, or for raising the specific antibodies, for the validation of anti-Zika Envelope antibodies, in vaccine development and other validation assays. This VLP can also be detected by the anti-C-terminal 6His-tag antibody.
The VLP’s titer was measured via ELISA P24 assay. Every single particle assembled many Zika Envelope molecules at its surface. See more details in Product Manual.
Amount: 200ul/vial at 1×108 VP/ml.
CAT#: VLP005
